Economic evaluations of personalized medicine: existing challenges and current developments
نویسندگان
چکیده
منابع مشابه
Economic evaluations of personalized medicine: existing challenges and current developments
Personalized medicine, with the aim of safely, effectively, and cost-effectively targeting treatment to a prespecified patient population, has always been a long-time goal within health care. It is often argued that personalizing treatment will inevitably improve clinical outcomes for patients and help achieve more effective use of health care resources. Demand is increasing for demonstrable ev...
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There is a need for methodological scrutiny in the economic assessment of personalized medicine. In this article, we present a list of 10 specific issues that we argue pose specific methodological challenges that require careful consideration when designing and conducting robust model-based economic evaluations in the context of personalized medicine. Key issues are related to the correct frami...
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Background Due to its epidemiological relevance, several studies have been performed to assess the cost-effectiveness of diagnostic tests and treatments in colorectal cancer (CRC) patients. Objective We reviewed economic evaluations on diagnosis of inherited CRC-syndromes and genetic tests for the detection of mutations associated with response to therapeutics. Methods A systematic literatu...
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ژورنال
عنوان ژورنال: Pharmacogenomics and Personalized Medicine
سال: 2015
ISSN: 1178-7066
DOI: 10.2147/pgpm.s35063